Doccol是(shi)一(yi)(yi)家美(mei)國生(sheng)物(wu)技術公司，從解決生(sheng)物(wu)研(yan)究(jiu)中(zhong)(zhong)(zhong)的(de)(de)(de)實(shi)際問(wen)題(ti)開始。2004年，Doccol發現(xian)(xian)了(le)實(shi)驗性卒中(zhong)(zhong)(zhong)研(yan)究(jiu)的(de)(de)(de)關鍵問(wen)題(ti)之一(yi)(yi)是(shi)卒中(zhong)(zhong)(zhong)模(mo)型(xing)的(de)(de)(de)質(zhi)(zhi)量不一(yi)(yi)致(zhi)(zhi)，因(yin)此(ci)通過(guo)提供標(biao)準化的(de)(de)(de)封(feng)堵(du)器，即(ji)硅橡膠(jiao)涂層單(dan)絲，用于大腦中(zhong)(zhong)(zhong)動(dong)脈閉(bi)塞（MCAO），為此(ci)提供了(le)解決方(fang)案(an)。這(zhe)些MCAO封(feng)堵(du)器深受中(zhong)(zhong)(zhong)風(feng)(feng)科(ke)(ke)研(yan)人(ren)員(yuan)的(de)(de)(de)喜愛，并被命名為“MCAO縫(feng)合(he)線(xian)"。 我(wo)們(men)精(jing)致(zhi)(zhi)的(de)(de)(de)硅橡膠(jiao)涂層單(dan)絲是(shi)專(zhuan)門(men)為誘導(dao)MCAO腔內燈絲模(mo)型(xing)而設計制(zhi)造(zao)的(de)(de)(de)，該模(mo)型(xing)已被廣泛用于體(ti)內實(shi)驗性腦卒中(zhong)(zhong)(zhong)研(yan)究(jiu)。使用 Doccol MCAO 縫(feng)合(he)線(xian)誘導(dao)卒中(zhong)(zhong)(zhong)模(mo)型(xing)將通過(guo)減(jian)少不全(quan)部閉(bi)塞和顱(lu)內出血的(de)(de)(de)發生(sheng)來提高(gao)模(mo)型(xing)質(zhi)(zhi)量。使用Doccol MCAO縫(feng)合(he)線(xian)，您(nin)將能(neng)夠(gou)實(shi)現(xian)(xian)高(gao)度一(yi)(yi)致(zhi)(zhi)的(de)(de)(de)梗(geng)死以及低死亡率。除了(le)認(ren)可的(de)(de)(de)產品質(zhi)(zhi)量外，Doccol還為MCAO縫(feng)合(he)線(xian)提供了(le)種類繁多(duo)的(de)(de)(de)縫(feng)合(he)線(xian)，旨在(zai)滿足中(zhong)(zhong)(zhong)風(feng)(feng)研(yan)究(jiu)人(ren)員(yuan)的(de)(de)(de)各種需求。多(duo)年來，我(wo)們(men)的(de)(de)(de)MCAO縫(feng)合(he)線(xian)一(yi)(yi)直被中(zhong)(zhong)(zhong)風(feng)(feng)研(yan)究(jiu)人(ren)員(yuan)優(you)選用于誘導(dao)中(zhong)(zhong)(zhong)風(feng)(feng)模(mo)型(xing)。據報道，使用Doccol MCAO縫(feng)合(he)線(xian)誘導(dao)MCAO模(mo)型(xing)能(neng)夠(gou)將梗(geng)死體(ti)積的(de)(de)(de)標(biao)準偏差降(jiang)低到(dao)其相應(ying)平均值的(de)(de)(de)5%; 這(zhe)種建模(mo)方(fang)法正(zheng)在(zai)成為確保MCAO模(mo)型(xing)最(zui)高(gao)質(zhi)(zhi)量的(de)(de)(de)新標(biao)準。欲了(le)解更多(duo)信息，中(zhong)(zhong)(zhong)國客戶請聯系(xi)美(mei)國Doccol在(zai)中(zhong)(zhong)(zhong)國的(de)(de)(de)總代理靶點科(ke)(ke)技。

2010年(nian)，Doccol注意(yi)到大(da)多數實(shi)驗室進(jin)行的(de)(de)(de)(de)(de)微(wei)(wei)血(xue)管(guan)導管(guan)插入(ru)術對于(yu)血(xue)液檢(jian)測(ce)和(he)藥(yao)物(wu)(wu)輸(shu)(shu)送都不方便。這些“微(wei)(wei)導管(guan)"有(you)一(yi)個需要針頭(tou)連(lian)接(jie)的(de)(de)(de)(de)(de)過渡管(guan)，當壓(ya)力高時(shi)可能會斷裂，并且可能會意(yi)外刺入(ru)操作員的(de)(de)(de)(de)(de)手指(zhi)，然后才能連(lian)接(jie)到合成器。這些導管(guan)也(ye)有(you)很大(da)的(de)(de)(de)(de)(de)內部容(rong)積(ji)，必須處理才能輸(shu)(shu)送藥(yao)物(wu)(wu)。Doccol 提供專門設計(ji)的(de)(de)(de)(de)(de)微(wei)(wei)導管(guan)，用(yong)于(yu)提高嚙(nie)齒(chi)動物(wu)(wu)血(xue)液采樣、藥(yao)物(wu)(wu)輸(shu)(shu)送、小流速液體(ti)(ti)轉移和(he)生(sheng)理監測(ce)的(de)(de)(de)(de)(de)性(xing)能、質(zhi)量和(he)生(sheng)產(chan)率，其中需要侵(qin)入(ru)性(xing)血(xue)管(guan)通(tong)路(lu)。我(wo)們(men)的(de)(de)(de)(de)(de)微(wei)(wei)導管(guan)連(lian)接(jie)到工業標準的(de)(de)(de)(de)(de)魯爾鎖或旋塞閥，因此消除了過渡管(guan)和(he)針頭(tou)連(lian)接(jie)，也(ye)大(da)大(da)減少了內部體(ti)(ti)積(ji)。Doccol 為(wei)所有(you)常見部位的(de)(de)(de)(de)(de)血(xue)管(guan)插管(guan)提供了足夠(gou)的(de)(de)(de)(de)(de)微(wei)(wei)導管(guan)選擇，例如尾靜(jing)(jing)脈(mo)(mo)、股靜(jing)(jing)脈(mo)(mo)、頸靜(jing)(jing)脈(mo)(mo)和(he)臂靜(jing)(jing)脈(mo)(mo)和(he)動脈(mo)(mo)，以及頸靜(jing)(jing)脈(mo)(mo)。

在Doccol多(duo)年(nian)來致力于(yu)中(zhong)風研(yan)究期(qi)間，Doccol 還開始提供(gong)精(jing)心挑選的基本(ben)顯微手術(shu)工具(ju)和(he)設備，并于(yu) 2019 年(nian)開發了其(qi)不同的基于(yu) Arduino 的 PID 溫度控制器。這些工具(ju)和(he)設備可(ke)確保您(nin)的實驗性中(zhong)風研(yan)究具(ju)有高質量和(he)高生(sheng)產率。

Doccol is a biotech company that started from solving real problems in biological research. In 2004, Doccol identified one of the key problems in experimental stroke research is the inconsistent quality of stroke models, and thence provided a solution for this by offerring standardized occluders, the silicone rubber-coated monofilaments,  for middle cerebral artery occlusion (MCAO). Those MCAO occluders  were liked very much by stroke reaearchers and given the name "MCAO sutures".  Our delicate silicone rubber-coated monofilaments are specially designed and manufactured for inducing the intraluminal filament model of MCAO, which has been widely used for in vivo experimental stroke studies. Using Doccol MCAO sutures for inducing stroke models will improve your model quality by reducing the occurrence of both the incomplete occlusion and the intracranial bleeding. With Doccol MCAO sutures, you will be able to achieve a highly consistent infarct as well as a low mortality rate. In addition to the super product quality, Doccol provides MCAO sutures with a great variety that was designed to meet the diverse demand from stroke investigators. For many years our MCAO sutures have been preferably selected by stroke investigators for inducing stroke models. Using Doccol MCAO sutures for inducing MCAO models has been reported to be able to reduce the standard deviation to 5% of its corresponding mean value as for infarction volume; and this modeling method is becoming a methodological new standard for ensuring the highest quality of MCAO models. For more information please read Doccol Made a Difference in Stroke Modeling.

In 2010, Doccol noticed that microvascular catheterization procedures performed in most laboratories are inconvinient for both blood testing and drug delivery. Those "microcatheters" have a transition tubing requiring a needle connection, which may break when pressure is high, and may accidentally puncture into the operator's finger, before it can be connected to a synringe. These catheters also have a large inner volume that has to be dealt with for drug delivery. Doccol offerred specially designed microcatheters for improving performance, quality and productivity in rodent blood sampling, drug delivery, small flow rate liquid transferring, and physiological monitoring, in which invasive vascular access is necessary. Our microcatheters are permanently connected to an industrial standard Luer lock or stopcock, therefore, eliminated the transitional tubing and needle connection and also dramatically reduced inner volume. Doccol provides sufficient choices of micro catheters for vascular cannulation in all common locations, such as the tail, femoral, carotid, and brachial veins and arteries, and also the jugular veins.

During years of our dedicated services in stroke research, Doccol also started to provide our carefully-selected essential microsurgical tools and devices, and in 2019 Doccol developed its unique Arduino-based PID temperature controllers. These essential tools and devices ensure your experimental stroke research with high quality and high productivity.

靶點科技（北京）有限公(gong)(gong)司(si)（Target Technology (Beijing) Co.,Ltd.），成(cheng)立(li)于(yu)2016年，是由一群來自(zi)歐洲荷蘭的留學海歸和(he)高校及研究所博士人員創辦的生物高科技公(gong)(gong)司(si)。公(gong)(gong)司(si)基于(yu)四個平臺技術TargoSome^®（脂質體靶向技(ji)術），TargoChem^®（化合物靶向技(ji)術(shu)），TargoAnti^®（抗(kang)體靶向技術）和TargoNano^®（納(na)米靶向(xiang)(xiang)技術），研(yan)發(fa)了靶向(xiang)(xiang)細胞的遞(di)送系(xi)統。

公司注重轉化(hua)醫學，強化(hua)“Bench-to-Bedside"的基礎產品開發。目前，靶點科技已經成為(wei)單核巨(ju)噬(shi)細胞(bao)系統研究領(ling)域的(de)(de)樹立良(liang)好口碑，能夠給研究人員提供各種模(mo)擬人類疾病(bing)的(de)(de)動物模(mo)型的(de)(de)制(zhi)備，公司團(tuan)隊對單核巨(ju)噬(shi)細胞(bao)系統有著深刻的(de)(de)認識和(he)理解，從(cong)標(biao)記(ji)，分離，富集，純化(hua)，培養和(he)細胞(bao)清(qing)除，形態識別(bie)等提供一整套綜合(he)解決方案。

基于對靶點科技（北京）有限公司的認同，自2022年11月29日期，靶點科技被美國Doccol公司授權為中國總代理。客戶通過靶點科技購買美國Doccol公(gong)司(si)的產品，質量可靠，渠道合法，售后無憂。大(da)腦中(zhong)動(dong)脈阻(zu)塞(MCAO)造模是(shi)研究(jiu)缺血(xue)性(xing)腦卒(zu)中的經典動物模型，Doccol是MCAO造模國際廣(guang)泛使用的栓(shuan)線品牌，文獻(xian)數以萬計。

靶點科技始終秉承“Bench to Bedside"的出(chu)發點，“專(zhuan)業(ye)⁺專(zhuan)注(zhu)⁺"的服務宗旨(zhi)，以(yi)“Hit Your Target^®"為(wei)目標， 竭力為(wei)客戶提供“Proven and Published^®"的一攬子綜合解決方案，將為(wei)實現(xian)這一美好(hao)愿景而努力奮斗。